Article
Uncoupling protein 3 and peroxisome proliferator-activated receptor gamma2 contribute to obesity and diabetes in palauans.
Biochemical and biophysical research communications - 2 Mar 2001
Yanagisawa Y, Hasegawa K, Dever G J, Otto C T, Sakuma M, Shibata S, Miyagi S, Kaneko Y, Kagawa Y
Abstract excerpt
We examined the genetic contribution of single nucleotide polymorphisms (SNPs) of the energy metabolism-related genes, including beta 3 adrenergic receptor (beta3AR), apolipoprotein E (apo-E), promoter of uncoupling protein 3 (UCP3-p), peroxisome proliferator-activated receptor gamma 2 (PPARgamma2) and leptin receptor (LEPR) to metabolic disorders, in 118 inhabitants of Palau. The data were statistically analyzed...
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