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Article

Association of an APOC3 promoter variant with type 2 diabetes risk and need for insulin treatment in lean persons.

Diabetologia - 1 Jun 2011

van Hoek M, van Herpt T W, Dehghan A, Hofman A, Lieverse A G, van Duijn C M, Witteman J C M, Sijbrands E J G

Abstract excerpt

AIMS/HYPOTHESIS: An APOC3 promoter haplotype has been previously associated with type 1 diabetes. In this population-based study, we investigated whether APOC3 polymorphisms increase type 2 diabetes risk and need for insulin treatment in lean participants. METHODS: In the Rotterdam Study, a population-based prospective cohort (n = 7,983), Cox and logistic regression models were used to analyse the associations...

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Share to Apolipoprotein C-III
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21373834
DOI: 10.1007/s00125-011-2092-x
PMCID: PMC3088807

Genes

APOC3

Provenance

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