Article
Polymorphic Variants rs3088442 and rs2292334 in the Organic Cation Transporter 3 (OCT3) Gene and Susceptibility Against Type 2 Diabetes: Role of their Interaction.
Archives of medical research - 1 Feb 2017
Mahrooz Abdolkarim, Alizadeh Ahad, Hashemi-Soteh Mohammad Bagher, Ghaffari-Cherati Maryam, Hosseyni-Talei Seyyedeh Raheleh
Abstract excerpt
AIMS: In this study, we investigated whether two common variants (rs3088442G>A and rs2292334G>A) in the organic cation transporter 3 (OCT3) gene, a high-capacity transporter widely expressed in various tissues, affect susceptibility to type 2 diabetes (T2D) in patients newly diagnosed with T2D. METHODS: We performed a study with 150 newly diagnosed patients with T2D and 152 controls. The genetic analyses were...
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