Article
A phosphomimetic mutation in the Sall1 repression motif disrupts recruitment of the nucleosome remodeling and deacetylase complex and repression of Gbx2.
The Journal of biological chemistry - 30 Nov 2007
Lauberth Shannon M, Bilyeu Amy C, Firulli Beth A, Kroll Kristen L, Rauchman Michael
Abstract excerpt
The multizinc finger transcription factor Sall1 is a critical developmental regulator that mediates repression through the recruitment of the nucleosome remodeling and deacetylase (NuRD) complex. Although a short conserved peptide motif in Sall1 is sufficient to recruit NuRD, its ability to regul...
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