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Article

Chronic alcohol ingestion alters claudin expression in the alveolar epithelium of rats.

Alcohol (Fayetteville, N.Y.) - 1 Aug 2007

Fernandez Alberto L, Koval Michael, Fan Xian, Guidot David M

Abstract excerpt

Previously we determined that chronic alcohol ingestion (6 weeks) in rats increases lung epithelial permeability in vivo approximately 5-6-fold and promotes flooding of the alveolar airspaces with proteinaceous fluid in response to stresses such as sepsis. In parallel, alveolar epithelial cells isolated from alcohol-fed rats fail to form tight monolayers in vitro, even when cultured for up to 8 days in the...

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Identifiers

PMID: 17889313
DOI: 10.1016/j.alcohol.2007.04.010
PMCID: PMC2048749

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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