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Article

Electroporation-mediated Gene Transfer of the Na + ,K + -ATPase Rescues Endotoxin-induced Lung Injury

7 Jun 2007

Abstract excerpt

RATIONALE: Acute lung injury and acute respiratory distress syndrome are common clinical syndromes resulting largely from the accumulation of and inability to clear pulmonary edema, due to injury to the alveolar epithelium. Gene therapy may represent an important alternative for the treatment and prevention of these diseases by restoring alveolar epithelial function. We have recently developed an electroporation...

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PMID: 17556717
DOI: 10.1164/rccm.200608-1246oc

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