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Article

Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jan 2005

Chen Stephen P, Zhou Beiyun, Willis Brigham C, Sandoval Argelia J, Liebler Janice M, Kim Kwang-Jin, Ann David K, Crandall Edward D, Borok Zea

Abstract excerpt

Rat alveolar epithelial type II cells grown on polycarbonate filters form high-resistance monolayers and concurrently acquire many phenotypic properties of type I cells. Treatment with EGF has previously been shown to increase transepithelial resistance across alveolar epithelial cell (AEC) monolayers. We investigated changes in claudin expression in primary cultured AEC during transdifferentiation to the type I...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Gene Expression Regulation, Developmental

Share to Protein Isoforms

Share to Pulmonary Alveoli

Share to Rats, Sprague-Dawley

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Source

Identifiers

PMID: 15361518
DOI: 10.1152/japplphysiol.00681.2004

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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