Article
Identification of the Drosophila eIF4A gene as a target of the DREF transcription factor.
Experimental cell research - 10 Dec 2007
Ida Hiroyuki, Yoshida Hideki, Nakamura Kumi, Yamaguchi Masamitsu
Abstract excerpt
The DNA replication-related element-binding factor (DREF) regulates cell proliferation-related gene expression in Drosophila. We have carried out a genetic screening, taking advantage of the rough eye phenotype of transgenic flies that express full-length DREF in the eye imaginal discs and identified the eukaryotic initiation factor 4A (eIF4A) gene as a dominant suppressor of the DREF-induced rough eye phenotype....
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