Article
Transcriptional regulation of the Drosophila moira and osa genes by the DREF pathway.
Nucleic acids research - 1 Jul 2008
Nakamura Kumi, Ida Hiroyuki, Yamaguchi Masamitsu
Abstract excerpt
The DNA replication-related element binding factor (DREF) plays an important role in regulation of cell proliferation in Drosophila, binding to DRE and activating transcription of genes carrying this element in their promoter regions. Overexpression of DREF in eye imaginal discs induces a rough eye phenotype in adults, which can be suppressed by half dose reduction of the osa or moira (mor) genes encoding...
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