Article
Transcriptional regulation of the Drosophila rfc1 gene by the DRE-DREF pathway.
The FEBS journal - 1 Apr 2007
Tsuchiya Akihiro, Inoue Yoshihiro H, Ida Hiroyuki, Kawase Yukari, Okudaira Koji, Ohno Katsuhito, Yoshida Hideki, Yamaguchi Masamitsu
Abstract excerpt
The DNA replication-related element (DRE) is a common 8-bp sequence (5'-TATCGATA) found in the promoters of many DNA replication-related genes, to which DRE-binding factor (DREF) specifically binds to activate transcription. Replication factor C (RFC) is an essential five-subunit complex in DNA replication, the largest subunit being RFC140. We first identified the gene (rfc1) encoding the Drosophila RFC140...
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