Article
Identification of the Drosophila skpA gene as a novel target of the transcription factor DREF.
Experimental cell research - 1 Nov 2006
Phuong Thao Dang Thi, Ida Hiroyuki, Yoshida Hideki, Yamaguchi Masamitsu
Abstract excerpt
SKPa is component of a Drosophila SCF complex that functions in combination with the ubiquitin-conjugating enzyme UbcD1. skpA null mutation results in centrosome overduplication, unusual chromatin condensation, defective endoreduplication and cell-cycle progression. While the molecular mechanisms that regulate expression of the skpA gene are poorly understood, the DNA replication-related element (DRE) and the...
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