Article
Transcriptional regulation of a new variant of human platelet-derived growth factor receptor alpha transcript by E2F-1.
Gene - 15 Nov 2007
Minato Yusuke, Tashiro Etsu, Kanai Mai, Nihei Yoshiaki, Kodama Yuki, Imoto Masaya
Abstract excerpt
Platelet-derived growth factors (PDGFs) and their receptors play an important role in cell proliferation, angiogenesis, and differentiation during normal development, and have also been implicated in tumorigenesis. In this study, we identified a novel variant of human PDGF receptor alpha mRNA (type II), which contains the same open reading frame as the known PDGF receptor alpha mRNA (type I) but a different...
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