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Article

Platelet-derived growth factor receptor alpha in glioma: a bad seed

1 Sept 2011

Abstract excerpt

Recent collaborative, large-scale genomic profiling of the most common and aggressive brain tumor glioblastoma multiforme(GBM) has significantly advanced our understanding of this disease. The gene encoding platelet-derived growth factor receptor alpha(PDGFRα) was identified as the third of the top 11 amplified genes in clinical GBM specimens. The important roles of PDGFRα signaling during normal brain...

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PMID: 21880180
DOI: 10.5732/cjc.011.10236

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