Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

P518/Qrfp sequence polymorphisms in SAMP6 osteopenic mouse.

Genomics - 1 Nov 2007

Zhang Qing, Qiu Ping, Arreaza M Gladys, Simon Jason S, Golovko Andrei, Laverty Maureen, Vassileva Galya, Gustafson Eric L, Rojas-Triana Alberto, Bober Loretta A, Hedrick Joseph A, Monsma Frederick J, Greene Jonathan R, Bayne Marvin L, Murgolo Nicholas J

Abstract excerpt

Mice lacking GPR103A expression display osteopenia. Analysis of mouse quantitative trait loci literature associated with bone mineral density suggested GPR103A ligand P518/Qrfp (chromosome 2qB) as a candidate osteoporosis gene. Promoter and coding regions of mouse P518/Qrfp were sequenced from genomic DNA obtained from the osteoporosis-prone strain SAMP6 and control strains SAMR1, A/J, AKR/J, BALB/c, C3H/HeJ,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Bone Diseases, Metabolic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intercellular Signaling Peptides and Proteins

Share to Mice, Inbred Strains

Share to Open Reading Frames

Share to Quantitative Trait, Heritable

Share to Receptors, G-Protein-Coupled

Share to Tissue Distribution

Source

Identifiers

PMID: 17869477
DOI: 10.1016/j.ygeno.2007.07.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

P518/Qrfp sequence polymorphisms in SAMP6 osteopenic mouse.PMID 17869477Read ↗

GPR98/Gpr98 gene is involved in the regulation of human and mouse bone mineral density.Semantic proximity Read ↗

The Sam68 STAR RNA-binding protein regulates mTOR alternative splicing during adipogenesis.Semantic proximity Read ↗

Mutations on a novel brain-specific isoform of PGC1α leads to extensive upregulation of neurotransmitter-related genes and sexually dimorphic motor deficits in miceSemantic proximity Read ↗

ADGRG6 promotes adipogenesis and is involved in sex-specific fat distributionSemantic proximity Read ↗

Evaluation of steroid receptor function by gene targeting in mice.Semantic proximity Read ↗

GPRC6A null mice exhibit osteopenia, feminization and metabolic syndrome.Semantic proximity Read ↗

Genes influencing spinal bone mineral density in inbred F344, LEW, COP, and DA rats.Semantic proximity Read ↗

An animal model for Pierpont syndrome: a mouse bearing the Tbl1xr1Y446C/Y446C mutation.Semantic proximity Read ↗

No evidence for a bone phenotype in GPRC6A knockout mice under normal physiological conditions.Semantic proximity Read ↗

A novel locus on the X chromosome regulates post-maturity bone density changes in mice.Semantic proximity Read ↗

Single nucleotide polymorphisms in sFRP4 are associated with bone and body composition related parameters in Danish but not in Belgian men.Semantic proximity Read ↗

Exploring Adaptive Phenotypes for the Human Calcium-Sensing Receptor Polymorphism R990G.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.