Article
GPR98/Gpr98 gene is involved in the regulation of human and mouse bone mineral density.
The Journal of clinical endocrinology and metabolism - 1 Apr 2012
Urano Tomohiko, Shiraki Masataka, Yagi Hideshi, Ito Masako, Sasaki Noriko, Sato Makoto, Ouchi Yasuyoshi, Inoue Satoshi
Abstract excerpt
CONTEXT: Genetic factors are important in the development of osteoporosis. OBJECTIVE: The aim of this study was to search for novel genes that regulate bone mineral density (BMD). DESIGN: We performed a search for 57,244 single-nucleotide polymorphisms (SNP) associated with BMD using SNP arrays and a replication study. SETTING AND PATIENTS: Baseline examinations were conducted in Japanese postmenopausal women....
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