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Article

Exploring Adaptive Phenotypes for the Human Calcium-Sensing Receptor Polymorphism R990G.

Molecular biology and evolution - 1 Feb 2024

Sinigaglia Barbara, Escudero Jorge, Biagini Simone A, Garcia-Calleja Jorge, Moreno Josep, Dobon Begoña, Acosta Sandra, Mondal Mayukh, Walsh Sandra, Aguileta Gabriela, Vallès Mònica, Forrow Stephen, Martin-Caballero Juan, Migliano Andrea Bamberg, Bertranpetit Jaume, Muñoz Francisco J, Bosch Elena

Abstract excerpt

Rainforest hunter-gatherers from Southeast Asia are characterized by specific morphological features including a particularly dark skin color (D), short stature (S), woolly hair (W), and the presence of steatopygia (S)-fat accumulation localized in the hips (DSWS phenotype). Based on previous evidence in the Andamanese population, we first characterized signatures of adaptive natural selection around the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38285634
DOI: 10.1093/molbev/msae015
PMCID: PMC10859840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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