Article
Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase.
Alcoholism, clinical and experimental research - 1 Nov 2007
Foroud Tatiana, Wetherill Leah Flury, Dick Danielle M, Hesselbrock Victor, Nurnberger John I, Kramer John, Tischfield Jay, Schuckit Marc, Bierut Laura J, Xuei Xiaoling, Edenberg Howard J
Abstract excerpt
OBJECTIVE: To test whether variation in the gene encoding the enzyme catechol-O-methyltransferase (COMT), which catalyzes the breakdown of dopamine and other catecholamine neurotransmitters, is associated with the risk for alcohol dependence and habitual smoking. METHODS: Single nucleotide polymo...
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