Article
Sex differences in the influence of COMT Val158Met on alcoholism and smoking in plains American Indians.
Alcoholism, clinical and experimental research - 1 Mar 2006
Enoch Mary-Anne, Waheed Juwaria F, Harris Claudia R, Albaugh Bernard, Goldman David
Abstract excerpt
BACKGROUND: Alcoholism and heavy smoking are highly comorbid and are cotransmitted in the general U.S. population; however little is known about comorbidity in American Indians. The catechol-O-methyltransferase (COMT) functional polymorphism, Val158Met, has been associated with alcoholism in Caucasians. The aims of our study were firstly to investigate patterns of alcohol and tobacco consumption and comorbidity...
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