Article
Effects of toll-like receptor-4 gene polymorphisms on soluble P-selectin and von Willebrand factor levels in hypercholesterolemic patients.
Thrombosis and haemostasis - 1 Sept 2007
Di Nisio Marcello, Di Febbo Concetta, Moretta Valeria, Guglielmi Maria Domenica, Stuppia Liborio, Cuccurullo Franco, Porreca Ettore
Abstract excerpt
Toll-like receptor-4 (TLR-4) gene polymorphisms have been associated with a lower risk of atherosclerosis. High levels of soluble P-selectin (sP-selectin) and von Willebrand factor predict an increased risk for cardiovascular events and correlate to atherosclerotic risk factors. The relationship between these markers and TLR-4 gene polymorphisms was evaluated in a cohort of consecutive hypercholesterolemic...
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