Article
The single nucleotide polymorphism Ser128Arg in the E-selectin gene is associated with enhanced coagulation during human endotoxemia.
Blood - 15 Mar 2005
Jilma Bernd, Marsik Claudia, Kovar Florian, Wagner Oswald F, Jilma-Stohlawetz Petra, Endler Georg
Abstract excerpt
The single nucleotide polymorphism (SNP) Ser128Arg in the E-selectin gene is overrepresented in certain patient groups with atherosclerosis or restenosis. We hypothesized and tested whether it may affect cytokine-induced levels of soluble (s) E-selectin, or be associated with proinflammatory or procoagulant properties in a well-standardized inflammation model. Healthy male volunteers (n = 157) received a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
