Article
Genetic variants in platelet factor 4 modulate inflammatory and platelet activation biomarkers.
Circulation. Cardiovascular genetics - 1 Aug 2012
Bhatnagar Pallav, Lu Xiaochun, Evans Michele K, Laveist Thomas A, Zonderman Alan B, Carter Darryl L, Arking Dan E, Fletcher Craig A
Abstract excerpt
BACKGROUND: African Americans suffer from higher prevalence and severity of atherosclerosis compared with whites, highlighting racial and ethnic disparities in cardiovascular disease. Previous studies have pointed to the role of vascular inflammation and platelet activation in the formation of atherosclerotic lesions. METHODS AND RESULTS: We explored the role of genetic variation in 4 chemokine/chemokine receptor...
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