Article
Interleukin-6 -174 G/C promoter polymorphism and effects of fenofibrate and simvastatin on inflammatory markers in hypercholesterolemic patients.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2006
Potaczek Daniel P, Undas Anetta, Celinska-Lowenhoff Magdalena, Szczeklik Andrew
Abstract excerpt
To evaluate whether the interleukin-6 (IL-6) -174 G/C polymorphism might alter the effects of micronized fenofibrate or simvastatin therapy on inflammatory markers, we measured IL-6, C-reactive protein, CD40 ligand, adhesion molecules, P-selectin and monocyte chemoattractant protein-1 in hypercholesterolemic patients both before and after a 30-day treatment. Serum IL-6 levels were significantly higher in patients...
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