Article
The MBL2 'LYQA secretor' haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery.
Circulation - 11 Sept 2007
Collard Charles D, Shernan Stanton K, Fox Amanda A, Bernig Toralf, Chanock Stephen J, Vaughn William K, Takahashi Kazue, Ezekowitz Alan B, Jarolim Petr, Body Simon C
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) is an important component of innate immunity and activator of the lectin complement pathway. Within the MBL2 gene are seven 5' "secretor" haplotypes that code for altered serum MBL levels and complement activation. However, recent evidence suggests that 3'...
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