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Article

Functional mannose-binding lectin haplotype variants are associated with Alzheimer's disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Sjölander Annica, Minthon Lennart, Nuytinck Lieve, Vanmechelen Eugeen, Blennow Kaj, Nilsson Staffan

Abstract excerpt

Mannan-Binding lectin (MBL) is a serum lectin and an important constituent of the innate immune system. Processes linked to the innate immune response have previously been implicated in Alzheimer's disease (AD). MBL is associated with blood vessels in the brain and AD patients demonstrate lower MBL levels in the cerebrospinal fluid compared to controls. We investigated six single nucleotide polymorphisms, linked...

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Source

Identifiers

PMID: 23348713
DOI: 10.3233/JAD-122044

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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