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Article

Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation.

Experimental hematology - 1 Oct 2006

Granell Miquel, Urbano-Ispizua Alvaro, Suarez Belén, Rovira Montserrat, Fernández-Avilés Francesc, Martínez Carmen, Ortega Mar, Uriburu Carla, Gaya Anna, Roncero Josep M A, Navarro Alfons, Carreras Enric, Mensa Josep, Vives Jordi, Rozman Ciril, Montserrat Emili, Lozano Francisco

Abstract excerpt

OBJECTIVE: The Mannan-binding lectin (MBL) pathway involves recognition of fungal surfaces by MBL and cleavage of C2 and C4 by MBL-associated serine protease (namely, MASP-2). Recent data show that MBL pathway deficiency might result not only from polymorphisms of the MBL2 gene but also of MASP2. The aim of the study was to assess whether polymorphisms of these genes are associated with invasive fungal infections...

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Source

Identifiers

PMID: 16982337
DOI: 10.1016/j.exphem.2006.06.005

Genes

MASP2
MBL2
SCT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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