Article
Prospective analysis of mannose-binding lectin genotypes and coronary artery disease in American Indians: the Strong Heart Study.
Circulation - 3 Feb 2004
Best Lyle G, Davidson Michael, North Kari E, MacCluer Jean W, Zhang Ying, Lee Elisa T, Howard Barbara V, DeCroo Susan, Ferrell Robert E
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) is a circulating immune factor responsible for opsonization of pathogens and directly activating complement. Common variations in the MBL gene are responsible for an opsonic deficiency that affects 5% to 7% of whites and are associated with increased susceptibility to infections. After a preliminary report associating these variations with coronary artery disease (CAD), we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
