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Article

Mannose binding lectin 2 haplotypes do not affect the progression of coronary atherosclerosis in men with proven coronary artery disease treated with pravastatin.

Atherosclerosis - 1 Mar 2011

Alipour Arash, Cabezas Manuel Castro, Elte Jan Willem F, Vallvé Joan-Carles, Ribalta Josep, Zwinderman Aeilko H, Defesche Joep C, Jukema J Wouter

Abstract excerpt

OBJECTIVE: Mannose binding lectin (MBL) is one of the three initiators of complement activation. Polymorphisms of the MBL2 gene and its promoter, and especially haplotypes, determine MBL plasma levels. MBL deficiency has been associated with the development of atherosclerosis. We evaluated whether the rate of angiographic progression of coronary atherosclerosis during pravastatin treatment was associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21211797
DOI: 10.1016/j.atherosclerosis.2010.11.041

Genes

MBL2
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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