Article
Low Mannose-Binding Lectin (MBL) genotype is associated with future cardiovascular events in type 2 diabetic South Asians. A prospective cohort study.
Cardiovascular diabetology - 5 Jul 2011
Siezenga Machiel A, Shaw Prataap K Chandie, Daha Mohamed R, Rabelink Ton J, Berger Stefan P
Abstract excerpt
BACKGROUND: South Asians have a high burden of type 2 diabetes and vascular complications. Vascular inflammation is considered central in the pathophysiology of atherosclerosis, and the complement system is thought to play an important role. Mannose-Binding Lectin (MBL), which activates the lectin pathway of complement activation, has been introduced as a risk marker of vascular damage. The present study explores...
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