Article
Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery.
Circulation - 4 Jul 2006
Podgoreanu M V, White W D, Morris R W, Mathew J P, Stafford-Smith M, Welsby I J, Grocott H P, Milano C A, Newman M F, Schwinn D A
Abstract excerpt
BACKGROUND: The inflammatory response triggered by cardiac surgery with cardiopulmonary bypass (CPB) is a primary mechanism in the pathogenesis of postoperative myocardial infarction (PMI), a multifactorial disorder with significant inter-patient variability poorly predicted by clinical and proce...
Topics
- Aged
- Alleles
- Cardiac Surgical Procedures
- Cardiopulmonary Bypass
- Cohort Studies
- E-Selectin
- Elective Surgical Procedures
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Intercellular Adhesion Molecule-1