Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mannose-binding lectin deficiency is associated with myocardial infarction: the HUNT2 study in Norway.

PloS one - 1 Jan 2012

Vengen Inga Thorsen, Madsen Hans O, Garred Peter, Platou Carl, Vatten Lars, Videm Vibeke

Abstract excerpt

OBJECTIVES: Mannose-binding lectin (MBL) and ficolins activate the complement cascade, which is involved in atherogenesis. Based on a pilot study, we hypothesized that functional polymorphisms in the MBL gene (MBL2) leading to dysfunctional protein are related to development of myocardial infarction (MI). The aim of the present study was to study polymorphisms in MBL2 and ficolin genes in relation to the risk of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Predisposition to Disease
Share to Haplotypes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Logistic Models

Share to Mannose-Binding Lectin

Share to Myocardial Infarction

Share to Norway

Share to Plaque, Atherosclerotic

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 22848725
DOI: 10.1371/journal.pone.0042113
PMCID: PMC3407165

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mannose-binding lectin deficiency is associated with myocardial infarction: the HUNT2 study in Norway.PMID 22848725Read ↗

Genetically-defined deficiency of mannose-binding lectin is associated with protection after experimental stroke in mice and outcome in human stroke.Semantic proximity Read ↗

Mannose-binding lectin genotype and phenotype in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial.Semantic proximity Read ↗

MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement.Semantic proximity Read ↗

Mannose-binding lectin gene polymorphism and risk factors for cardiovascular disease in postmenopausal women.Semantic proximity Read ↗

The MBL2 'LYQA secretor' haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery.Semantic proximity Read ↗

Characterization of mannose-binding lectin (MBL) variants by allele-specific sequencing of MBL2 and determination of serum MBL protein levels.Semantic proximity Read ↗

Genetic and other factors determining mannose-binding lectin levels in American Indians: the Strong Heart Study.Semantic proximity Read ↗

Mannose-binding lectin genotypes and pre-eclampsia: a case-control study.Semantic proximity Read ↗

Coding and non-coding polymorphisms in the lectin pathway activator L-ficolin gene in 188 Dutch blood bank donors.Semantic proximity Read ↗

A population-based study of morbidity and mortality in mannose-binding lectin deficiency.Semantic proximity Read ↗

Association of mannose-binding lectin genotype with cardiovascular abnormalities in Kawasaki disease.Semantic proximity Read ↗

Mannose-binding lectin 2 gene and risk of adult glioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.