Article
Evolution of hepatitis C virus non-structural 5A gene in the progression of liver disease to hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Oct 2007
De Mitri Maria Stella, Cassini Romina, Bagaglio Sabrina, Morsica Giulia, Andreone Pietro, Marino Nicoletta, Bernardi Mauro
Abstract excerpt
BACKGROUND: The interaction between the hepatitis C virus (HCV) non-structural 5A (NS5A) protein of HCV and the protein kinase R (PKR), which is an effector of the cellular antiviral response and has been defined as a tumour suppressor, may affect the control of protein synthesis and cell growth....
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