Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progression of Fibrosis during Chronic Hepatitis C Is Associated with Rapid Virus Evolution

1 Mar 2007

Abstract excerpt

Hepatic fibrosis is the primary mediator of disease due to chronic infection with hepatitis C virus (HCV). HCV exists as a quasispecies in each infected individual, and longitudinal viral sequence changes may reveal viral dynamics and the selection pressures applied by the host immune system. Thus, we hypothesized that patterns of sequence change might reveal the immunopathogenesis of fibrosis progression. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17329332
DOI: 10.1128/jvi.02276-06

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progression of Fibrosis during Chronic Hepatitis C Is Associated with Rapid Virus EvolutionPMID 17329332Read ↗

Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection.Semantic proximity Read ↗

Acceleration of Hepatitis C Virus Envelope Evolution in Humans Is Consistent with Progressive Humoral Immune Selection during the Transition from Acute to Chronic InfectionSemantic proximity Read ↗

Impact of common risk factors of fibrosis progression in chronic hepatitis C.Semantic proximity Read ↗

Genetic diversity of near genome-wide hepatitis C virus sequences during chronic infection: evidence for protein structural conservation over time.Semantic proximity Read ↗

Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome SequencingSemantic proximity Read ↗

Hepatitis C virus molecular evolution: transmission, disease progression and antiviral therapy.Semantic proximity Read ↗

Dynamic coinfection with multiple viral subtypes in acute hepatitis C.Semantic proximity Read ↗

Quantitative differences between intra-host HCV populations from persons with recently established and persistent infectionsSemantic proximity Read ↗

Exceptional Heterogeneity in Viral Evolutionary Dynamics Characterises Chronic Hepatitis C Virus InfectionSemantic proximity Read ↗

Longitudinal analysis of hepatitis C virus replication and liver fibrosis progression in renal transplant recipients.Semantic proximity Read ↗

Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C.Semantic proximity Read ↗

Genetics, Genomics, and Proteomics: Implications for the Diagnosis and the Treatment of Chronic Hepatitis CSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.