Article
Nonstructural 5A gene variability of hepatitis C virus (HCV) during a 10-year follow up.
Journal of gastroenterology - 1 Jan 2005
Fan Wenmei, Zhu Wanfu, Wei Lai, Wang Qixin, Yin Limin, Du Shaocai, Zhuang Hui
Abstract excerpt
BACKGROUND: Seven patients with chronic hepatitis C virus (HCV) infection were followed up for 10 years in order to analyze the molecular evolution of the HCV nonstructural 5A (NS5A) gene. METHODS: Serum samples were obtained from seven patients with anti-HCV who were HCV-RNA positive. The HCV NS5A region, including the interferon sensitivity-determining region (ISDR), protein kinase R binding domain (PKR-BD),...
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