Article
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.
Diabetes - 1 Dec 2007
Grarup Niels, Rose Chrisian S, Andersson Ehm A, Andersen Gitte, Nielsen Arne L, Albrechtsen Anders, Clausen Jesper O, Rasmussen Signe S, Jørgensen Torben, Sandbaek Annelli, Lauritzen Torsten, Schmitz Ole, Hansen Torben, Pedersen Oluf
Abstract excerpt
OBJECTIVE: In the present study, we aimed to validate the type 2 diabetes susceptibility alleles identified in six recent genome-wide association studies in the HHEX/KIF11/IDE (rs1111875), CDKN2A/B (rs10811661), and IGF2BP2 (rs4402960) loci, as well as the intergenic rs9300039 variant. Furthermor...
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