Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

doi:10.1007/s00125-010-2038-8

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Article

Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

Diabetologia - 1 Apr 2011

Hribal M L, Presta I, Procopio T, Marini M A, Stančáková A, Kuusisto J, Andreozzi F, Hammarstedt A, Jansson P-A, Grarup N, Hansen T, Walker M, Stefan N, Fritsche A, Häring H U, Pedersen O, Smith U, Laakso M, Sesti G

Abstract excerpt

AIMS/HYPOTHESIS: The aim of this study was to investigate the association of the rs10811661 polymorphism near the CDKN2B/CDKN2A genes with glucose tolerance, insulin sensitivity and insulin release in three samples of white people with European ancestry. METHODS: Sample 1 comprised 845 non-diabetic offspring of type 2 diabetes patients recruited in five European centres participating in the EUGENE2 study. Samples...

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PMID: 21234743
DOI: 10.1007/s00125-010-2038-8

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