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Article

Polymorphisms in the IDE-KIF11-HHEX gene locus are reproducibly associated with type 2 diabetes in a Japanese population.

The Journal of clinical endocrinology and metabolism - 1 Jan 2008

Furukawa Yasushi, Shimada Takeshi, Furuta Hiroto, Matsuno Shohei, Kusuyama Akiko, Doi Asako, Nishi Masahiro, Sasaki Hideyuki, Sanke Tokio, Nanjo Kishio

Abstract excerpt

CONTEXT: A genome-wide association study in the French population has detected that novel single-nucleotide polymorphisms (SNPs) in the IDE-KIF11-HHEX gene locus and the SLC30A8 gene locus are associated with susceptibility to type 2 diabetes. OBJECTIVE: We investigated whether SNPs in these loci were associated with type 2 diabetes in Japanese. DESIGN: Two SNPs, rs7923837 and rs1111875, in the IDE-KIF11-HHEX...

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Source

Identifiers

PMID: 17971426
DOI: 10.1210/jc.2007-1029

Genes

HHEX
IDE
KIF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in the IDE-KIF11-HHEX gene locus are reproducibly associated with type 2 diabetes in a Japanese population.PMID 17971426Read ↗

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Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population.Semantic proximity Read ↗

Variations in/nearby genes coding for JAZF1, TSPAN8/LGR5 and HHEX-IDE and risk of type 2 diabetes in Han Chinese.Semantic proximity Read ↗

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