Article
Genetic variants of IDE-KIF11-HHEX at 10q23.33 associated with type 2 diabetes risk: a fine-mapping study in Chinese population.
PloS one - 1 Jan 2012
Qian Yun, Lu Feng, Dong Meihua, Lin Yudi, Li Huizhang, Chen Jian, Shen Chong, Jin Guangfu, Hu Zhibin, Shen Hongbing
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) in populations of European ancestry have mapped a type 2 diabetes susceptibility region to chromosome 10q23.33 containing IDE, KIF11 and HHEX genes (IDE-KIF11-HHEX), which has also been replicated in Chinese populations. However, the functional relevance for genetic variants at this locus is still unclear. It is critical to systematically assess the relationship...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
