Article
Rab6 and the secretory pathway affect oocyte polarity in Drosophila.
Development (Cambridge, England) - 1 Oct 2007
Januschke Jens, Nicolas Emmanuelle, Compagnon Julien, Formstecher Etienne, Goud Bruno, Guichet Antoine
Abstract excerpt
The Drosophila oocyte is a highly polarized cell. Secretion occurs towards restricted neighboring cells and asymmetric transport controls the localization of several mRNAs to distinct cortical compartments. Here, we describe a role for the Drosophila ortholog of the Rab6 GTPase, Drab6, in establishing cell polarity during oogenesis. We found that Drab6 localizes to Golgi and Golgi-derived membranes and interacts...
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