Article
PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte.
Development (Cambridge, England) - 1 Dec 2008
Gervais Louis, Claret Sandra, Januschke Jens, Roth Siegfried, Guichet Antoine
Abstract excerpt
The attachment of the cytoskeleton to the plasma membrane is crucial in controlling the polarized transport of cell-fate-determining molecules. Attachment involves adaptor molecules, which have the capacity to bind to both the plasma membrane and elements of the cytoskeleton, such as microtubules and actin filaments. Using the Drosophila oocyte as a model system, we show that the type I phosphatidylinositol...
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