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Clinical and Molecular Genetic Analysis of Children with Severe Short Stature due to Isolated Growth Hormone Deficiency: Insights from a South Indian Cohort and Predictors of Growth Response.

2025-10-10

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<title>Abstract</title> <p> Purpose: Isolated growth hormone deficiency (IGHD) is one among the treatable causes of short stature. We aimed to describe the clinical, biochemical, and molecular characteristics of IGHD as well as to identify clinical predictors of mutation positivity and first-year height response to recombinant human growth hormone (rhGH). <h4>Methods:</h4> Sixty-three children with IGHD who had...

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Literature Corpus work: 1ba8b5a1-dc13-5e21-a75f-4fe6842150a6
DOI: 10.21203/rs.3.rs-7689542/v1

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