Article
GH Resistance Is a Component of Idiopathic Short Stature: Implications for rhGH Therapy.
Frontiers in endocrinology - 1 Jan 2021
Savage Martin O, Storr Helen L
Abstract excerpt
Idiopathic short stature (ISS) is a term used to describe a selection of short children for whom no precise aetiology has been identified. Molecular investigations have made notable discoveries in children with ISS, thus removing them from this category. However, many, if not the majority of children referred with short stature, are designated ISS. Our interest in defects of GH action, i.e. GH resistance, has led...
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