Article
ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.
Chinese medical journal - 1 Mar 2012
Chen Xiang-ding, Xiong Dong-hai, Yang Tie-lin, Pei Yu-fang, Guo Yan-fang, Li Jian, Yang Fang, Pan Feng, Tan Li-jun, Yan Han, Liu Xiao-gang, Lei Shu-feng, Li Xi, Ning Ling-ling, Zhu Xue-zhen, Levy Shawn, Kranzler Henry R, Farrer Lindsay A, Gelernter Joel, Recker Robert R, Deng Hong-wen
Abstract excerpt
BACKGROUND: Alcohol dependence (AD) is a complex disorder characterized by impaired control over drinking. It is determined by both genetic and environmental factors. The recent approach of genome-wide association study (GWAS) is a powerful tool for identifying complex disease-associated susceptibility alleles, however, a few GWASs have been conducted for AD, and their results are largely inconsistent. The...
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