Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GRASP-1 is a neuronal scaffold protein for the JNK signaling pathway.

FEBS letters - 18 Sept 2007

Ye Bing, Yu Wei-ping, Thomas Gareth M, Huganir Richard L

Abstract excerpt

GRASP-1 is a neuronally enriched protein that interacts with the AMPA-type glutamate receptor/GRIP complex. GRASP-1 can be cleaved by Caspase-3 in both normal and ischemic brains although the functional significance of this cleavage remains elusive. We investigated signal transduction pathways that might lie downstream of GRASP-1 and found that GRASP-1 potently activates JNK pathway signaling, with no effect on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to Caspase 3
Share to Extracellular Signal-Regulated MAP Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoprecipitation

Share to JNK Mitogen-Activated Protein Kinases

Share to MAP Kinase Kinase Kinase 1

Share to Mitogen-Activated Protein Kinase 8

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 17761173
DOI: 10.1016/j.febslet.2007.08.008
PMCID: PMC2720598

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GRASP-1 is a neuronal scaffold protein for the JNK signaling pathway.PMID 17761173Read ↗

GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA Receptors.Semantic proximity Read ↗

Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis.Semantic proximity Read ↗

ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood-brain barrier integrity after traumatic brain injurySemantic proximity Read ↗

PICK1 links KIBRA and AMPA receptors in coiled-coil-driven supramolecular complexesSemantic proximity Read ↗

Mkp1 is a c-Jun target gene that antagonizes JNK-dependent apoptosis in sympathetic neurons.Semantic proximity Read ↗

KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNASemantic proximity Read ↗

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase.Semantic proximity Read ↗

MINK and TNIK differentially act on Rap2-mediated signal transduction to regulate neuronal structure and AMPA receptor function.Semantic proximity Read ↗

Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosisSemantic proximity Read ↗

Neuroprotection against transient focal cerebral ischemia and oxygen-glucose deprivation by interference with GluR6-PSD95 protein interaction.Semantic proximity Read ↗

Genetic Mutation of GluN2B Protects Brain Cells Against Stroke Damages.Semantic proximity Read ↗

Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.