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Article

Neuroprotection against transient focal cerebral ischemia and oxygen-glucose deprivation by interference with GluR6-PSD95 protein interaction.

Neurochemical research - 1 Nov 2009

Yu Chang-Zhou, Li Chong, Pei Dong-Sheng, Zong Yan-Yan, Shi Qiong, Wen Xiang-Ru, Guan Qiu-Hua, Hang Dong, Hou Xiao-Yu, Zhang Guang-Yi

Abstract excerpt

Previous studies have shown that KA receptor subunit GluR6 mediated c-Jun N-terminal protein kinase (JNK) signaling is involved in global ischemia injury. Our present study indicates that focal ischemic brain insult on rat middle cerebral artery occlusion (MACo) model enhances the assembly of the GluR6-PSD95-MLK3 module and facilitates the phosphorylation of JNK. Most importantly, a peptide containing the TAT...

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Identifiers

PMID: 19449206
DOI: 10.1007/s11064-009-9990-z

Genes

TAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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