Article

ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood-brain barrier integrity after traumatic brain injury

2023-08-16

Abstract excerpt

<h4>Background: </h4> Traumatic brain injury (TBI) is a significant worldwide public health concern that necessitates attention. Apoptosis signal-regulating kinase 1 (ASK1), a key player in various central nervous system (CNS) diseases, has garnered interest for its potential neuroprotective effects against ischemic stroke and epilepsy when deleted. Nonetheless, the specific impact of ASK1 on TBI and its underlyin...

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Literature Corpus work: 57d9ab16-d678-5e2f-9643-1e1c12684aca
DOI: 10.21203/rs.3.rs-3250841/v1

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