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Article

nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells.

American journal of physiology. Cell physiology - 1 Nov 2007

Ehre Camille, Zhu Yunxiang, Abdullah Lubna H, Olsen John, Nakayama Keiichi I, Nakayama Keiko, Messing Robert O, Davis C William

Abstract excerpt

Airway goblet cell mucin secretion is controlled by agonist activation of P2Y(2) purinoceptors, acting through Gq/PLC, inositol-1,4,5-trisphosphate (IP(3)), diacylglycerol, Ca(2+) and protein kinase C (PKC). Previously, we showed that SPOC1 cells express cPKCalpha, nPKCdelta, nPKCepsilon, and nPKCeta; of these, only nPKCdelta translocated to the membrane in correlation with mucin secretion (Abdullah LH, Bundy JT,...

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Identifiers

PMID: 17728398
DOI: 10.1152/ajpcell.00051.2007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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