Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Barrier role of actin filaments in regulated mucin secretion from airway goblet cells

2 Sept 2004

Abstract excerpt

Airway goblet cells secrete mucin onto mucosal surfaces under the regulation of an apical, phospholipase C/G(q)-coupled P2Y(2) receptor. We tested whether cortical actin filaments negatively regulate exocytosis in goblet cells by forming a barrier between secretory granules and plasma membrane docking sites as postulated for other secretory cells. Immunostaining of human lung tissues and SPOC1 cells (an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Neonatal Respiratory Health Research
Share to Proteoglycans and glycosaminoglycans research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15342343
DOI: 10.1152/ajpcell.00397.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Barrier role of actin filaments in regulated mucin secretion from airway goblet cellsPMID 15342343Read ↗

nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells.Semantic proximity Read ↗

Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration.Semantic proximity Read ↗

Cofilin recruitment and function during actin-mediated endocytosis dictated by actin nucleotide state.Semantic proximity Read ↗

Intermediate filaments as effectors of differentiationSemantic proximity Read ↗

CD44 and β3 Integrin Organize Two Functionally Distinct Actin-based Domains in OsteoclastsSemantic proximity Read ↗

Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polaritySemantic proximity Read ↗

Mucins, Mucus, and Goblet CellsSemantic proximity Read ↗

CFTR and calcium-activated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype.Semantic proximity Read ↗

Compartmentalized Cyclic Adenosine 3′,5′-Monophosphate at the Plasma Membrane Clusters PDE3A and Cystic Fibrosis Transmembrane Conductance Regulator into MicrodomainsSemantic proximity Read ↗

Coupled Nucleotide and Mucin Hypersecretion from Goblet-Cell Metaplastic Human Airway EpitheliumSemantic proximity Read ↗

A reciprocal interdependence between Nck and PI(4,5)P(2) promotes localized N-WASp-mediated actin polymerization in living cells.Semantic proximity Read ↗

Cofilin promotes rapid actin filament turnover in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.