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Article

Rescue of defective pancreatic secretion in cystic-fibrosis cells by suppression of a novel isoform of phospholipase C.

Lancet (London, England) - 20 Dec 2003

Zhu Hu, Zhu Jin Xia, Lo Pui Shan, Li Jianmin, Leung Ka Man, Rowlands Dewi Kenneth, Tsang Lai Ling, Yu Mei Kuen, Jiang Jian Li, Lam Sun Yee, Chung Yiu Wa, Zhou Zuomin, Sha Jiahao, Chang Chan Hsiao

Abstract excerpt

BACKGROUND: Cystic fibrosis is caused by mutations in the gene encoding an ion-transport protein, the cystic-fibrosis transmembrane conductance regulator (CFTR). Defective secretion of anions is the primary cause of many of the clinical manifestations of cystic fibrosis, including pancreatic insu...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

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Source

Identifiers

PMID: 14697805
DOI: 10.1016/s0140-6736(03)15100-8

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14697805-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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