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Article

Gene conversion limits divergence of mammalian TLR1 and TLR6.

BMC evolutionary biology - 29 Aug 2007

Kruithof Egbert K O, Satta Nathalie, Liu Jia Wei, Dunoyer-Geindre Sylvie, Fish Richard J

Abstract excerpt

BACKGROUND: Toll-like receptors (TLR) recognize pathogen-associated molecular patterns and are important mediators of the innate immune system. TLR1 and TLR6 are paralogs and located in tandem on the same chromosome in mammals. They form heterodimers with TLR2 and bind lipopeptide components of gram-positive and gram-negative bacterial cell walls. To identify conserved stretches in TLR1 and TLR6, that may be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Toll-Like Receptor 1

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Source

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Identifiers

PMID: 17727694
DOI: 10.1186/1471-2148-7-148
PMCID: PMC2077338

Genes

TLR1
TLR6
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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