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Article

Identification of mutations that decrease the stability of a fragment of Saccharomyces cerevisiae chromosome III lacking efficient replicators.

Genetics - 1 Nov 2007

Theis James F, Dershowitz Ann, Irene Carmela, Maciariello Clelia, Tobin Michael L, Liberi Giordano, Tabrizifard Sahba, Korus Malgorzata, Fabiani Lucia, Newlon Carol S

Abstract excerpt

Eukaryotic chromosomes are duplicated during S phase and transmitted to progeny during mitosis with high fidelity. Chromosome duplication is controlled at the level of replication initiation, which occurs at cis-acting replicator sequences that are spaced at intervals of approximately 40 kb along the chromosomes of the budding yeast Saccharomyces cerevisiae. Surprisingly, we found that derivatives of yeast...

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Identifiers

PMID: 17720931
DOI: 10.1534/genetics.107.074690
PMCID: PMC2147994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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